New Research Highlights an Unusual Side Effect of GLP-1 Weight Loss Medications

Medications such as Ozempic, Wegovy and Mounjaro have changed the landscape of weight loss treatment in Australia and globally. These GLP-1 receptor agonists are increasingly prescribed for obesity and weight management, helping many people reduce appetite, regulate blood sugar and lose significant weight over time.

However, emerging research is now drawing attention to an unexpected issue. Recent findings suggest that GLP-1 weight loss drugs may interfere with certain types of medical imaging, particularly PET and CT scans. Researchers have observed that these medications can alter how the body absorbs glucose, which may affect scan results and, in some cases, lead to unnecessary additional testing.

 

How GLP-1 Medications May Affect Medical Imaging

GLP-1 medications work by slowing gastric emptying and influencing insulin and glucose regulation. PET scans often rely on glucose-based tracers to identify abnormal activity in the body. Because GLP-1 drugs can change glucose metabolism, imaging results may appear unusual or misleading.

This does not mean the medications are unsafe. It just highlights the importance of informing your medical team if you are using weight loss injections before undergoing diagnostic imaging. Clear communication between patients, GPs, specialists, and radiology providers is essential to avoid confusion and unnecessary follow-up tests.

As weight loss medication becomes more common in Australia, awareness of these interactions is increasingly important.

 

Medication vs Surgery: A Broader Conversation

At Perth Weight Loss & Surgery, we regularly speak with patients who are considering injections such as Ozempic, Wegovy or Mounjaro, as well as those exploring bariatric surgery options like gastric sleeve or gastric bypass.

Cost is often part of the discussion.

Currently, medications such as Wegovy and Ozempic range from approximately $250 to $360 per month. Mounjaro, which is often considered more effective for weight reduction, can range from $280 to $750 per month depending on dosage. On average, patients may spend around $400 to $500 per month. Over a year, this equates to approximately $5,000 or more in ongoing medication costs.

Surgical treatment, by comparison, involves a one-off procedural cost. For patients with appropriate private health insurance, the out-of-pocket cost can be similar to a year of medication. The difference is that surgery is not a monthly expense. It is a single procedure with structured follow-up care.

However, the most important factor is not cost alone. It is clinical suitability, safety and long-term outcomes.

 

Understanding Your Options

Both weight loss injections and bariatric surgery are valid medical treatments for obesity. The right pathway depends on your health history, BMI, metabolic conditions, lifestyle and long-term goals.

Weight loss medication can be an effective option for some individuals, particularly those seeking a non-surgical approach. Surgery may provide more durable long-term outcomes for others, especially in cases of severe obesity or obesity-related conditions such as type 2 diabetes, sleep apnoea or cardiovascular risk.

During your consultation at Perth Weight Loss & Surgery, we assess your medical history, current health status and personal goals before recommending a treatment pathway. Our multidisciplinary team, including dietitians and exercise physiologists, supports patients whether they pursue medication, surgery or a combination approach.

 

Informed Decisions Lead to Life-Changing Outcomes

The new research about GLP-1 medications and medical imaging is not a reason for alarm. It is a reminder that every treatment has considerations. The key is understanding your options fully and making decisions based on evidence, safety and long-term health.

Weight loss treatment can be life changing when you are informed, supported and guided by experienced professionals.

If you are considering weight loss medication or bariatric surgery in Perth, speak with our team to understand what pathway may be right for you.

It starts with clarity.